2,5-Hexanedione induces dopaminergic neurodegeneration through integrin α(M)β2/NADPH oxidase axis-mediated microglial activation

Recent study demonstrated that chronic exposure to solvents increases the risk of Parkinson’s disease (PD), the second most common neurodegenerative disorder characterized by progressive dopaminergic neurodegeneration in the substantia nigra (SN). n-Hexane, a widely used organic solvent, displays ce...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Zhang, Cong, Hou, Liyan, Yang, Jie, Che, Yuning, Sun, Fuqiang, Li, Huihua, Wang, Qingshan
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833449/
https://ncbi.nlm.nih.gov/pubmed/29352205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0091-7
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