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CFTR mutation enhances Dishevelled degradation and results in impairment of Wnt-dependent hematopoiesis
Mutations of cystic fibrosis transmembrane conductance regulator (CFTR) cause cystic fibrosis (CF) with a multitude of clinical manifestations. Some CF patients develop clinically significant anemia, suggesting that CFTR may regulate hematopoiesis. Here, we report that cftr mutant zebrafish model ex...
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Publicado no: | Cell Death Dis |
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Main Authors: | , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group UK
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5833403/ https://ncbi.nlm.nih.gov/pubmed/29449653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0311-9 |
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