CFTR Deletion in Mouse Testis Induces VDAC1 Mediated Inflammatory Pathway Critical for Spermatogenesis

Cystic fibrosis is the most common genetic disease among Caucasians and affects tissues including lung, pancreas and reproductive tracts. It has been shown that Endoplasmic Reticulum (ER) stress and heat shock response are two major deregulated functional modules related to CFTR dysfunction. To iden...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yan, Chen, Lang, Qin, Huijuan, Liao, Jiang, Xie, Ming, Yang, Huaqin, Sun, Wenming, Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970767/
https://ncbi.nlm.nih.gov/pubmed/27483469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158994
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