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Novel function of ceramide for regulation of mitochondrial ATP release in astrocytes
We reported that amyloid β peptide (Aβ(42)) activated neutral SMase 2 (nSMase2), thereby increasing the concentration of the sphingolipid ceramide in astrocytes. Here, we show that Aβ(42) induced mitochondrial fragmentation in wild-type astrocytes, but not in nSMase2-deficient cells or astrocytes tr...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Lipid Res |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The American Society for Biochemistry and Molecular Biology
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5832933/ https://ncbi.nlm.nih.gov/pubmed/29321137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M081877 |
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