Interplay between ChREBP and SREBP-1c coordinates postprandial glycolysis and lipogenesis in livers of mice

Lipogenesis in liver is highest in the postprandial state; insulin activates SREBP-1c, which transcriptionally activates genes involved in FA synthesis, whereas glucose activates carbohydrate-responsive element-binding protein (ChREBP), which activates both glycolysis and FA synthesis. Whether SREBP...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Linden, Albert G., Li, Shili, Choi, Hwa Y., Fang, Fei, Fukasawa, Masashi, Uyeda, Kosaku, Hammer, Robert E., Horton, Jay D., Engelking, Luke J., Liang, Guosheng
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832931/
https://ncbi.nlm.nih.gov/pubmed/29335275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M081836
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