PIP4K2A regulates intracellular cholesterol transport through modulating PI(4,5)P(2) homeostasis

The transport of LDL-derived cholesterol from lysosomes to peroxisomes is facilitated by membrane contacts formed between the lysosomal protein synaptotagmin VII and the peroxisomal lipid phosphatidylinositol 4, 5-bisphosphate [PI(4,5)P(2)]. Here, we used RNA interference to search for regulators of...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Hu, Ao, Zhao, Xue-Tong, Tu, Heng, Xiao, Ting, Fu, Ting, Wang, Yan, Liu, Yong, Shi, Xiong-Jie, Luo, Jie, Song, Bao-Liang
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832930/
https://ncbi.nlm.nih.gov/pubmed/29353240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M082149
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