25-Hydroxycholesterol activates the expression of cholesterol 25-hydroxylase in an LXR-dependent mechanism

Cholesterol 25-hydroxylase (CH25H) catalyzes the production of 25-hydroxycholesterol (25-HC), an oxysterol that can play an important role in different biological processes. However, the mechanisms regulating CH25H expression have not been fully elucidated. In this study, we determined that CH25H is...

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Vydáno v:J Lipid Res
Hlavní autoři: Liu, Ying, Wei, Zhuo, Ma, Xingzhe, Yang, Xiaoxiao, Chen, Yuanli, Sun, Lei, Ma, Chuanrui, Miao, Qing R., Hajjar, David P., Han, Jihong, Duan, Yajun
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2018
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832929/
https://ncbi.nlm.nih.gov/pubmed/29298812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M080440
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