Activation of liver X receptor plays a central role in antiviral actions of 25-hydroxycholesterol

Production of 25-hydroxycholesterol (25HC), a potent inhibitor of viral infection, is catalyzed by cholesterol 25-hydroxylase (CH25H). We previously reported that 25HC induced CH25H expression in a liver X receptor (LXR)-dependent manner, implying that LXR can play an important role in antiviral inf...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Liu, Ying, Wei, Zhuo, Zhang, Ye, Ma, Xingzhe, Chen, Yuanli, Yu, Miao, Ma, Chuanrui, Li, Xiaoju, Cao, Youjia, Liu, Jian, Han, Jihong, Yang, Xiaoxiao, Duan, Yajun
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277154/
https://ncbi.nlm.nih.gov/pubmed/30309895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M084558
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