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highroad Is a Carboxypetidase Induced by Retinoids to Clear Mutant Rhodopsin-1 in Drosophila Retinitis Pigmentosa Models

Rhodopsins require retinoid chromophores for their function. In vertebrates, retinoids also serve as signaling molecules, but whether these molecules similarly regulate gene expression in Drosophila remains unclear. Here, we report the identification of a retinoid-inducible gene in Drosophila, highr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Rep
Hauptverfasser: Huang, Huai-Wei, Brown, Brian, Chung, Jaehoon, Domingos, Pedro M., Ryoo, Hyung Don
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832065/
https://ncbi.nlm.nih.gov/pubmed/29425495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.01.032
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