Učitavanje...
Cdk5 and Mekk1 mediate a Pro-Apoptotic Signaling Response to Endoplasmic Reticulum Stress in a Drosophila Model of Autosomal Dominant Retinitis Pigmentosa
Chronic stress in the endoplasmic reticulum (ER) underlies many degenerative and metabolic diseases involving apoptosis of vital cells. A well-established example is Autosomal Dominant Retinitis Pigmentosa (ADRP), an age-related retinal degenerative disease caused by mutant rhodopsins (1, 2). Simila...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3319494/ https://ncbi.nlm.nih.gov/pubmed/22388889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2447 |
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