Dimerization deficiency of enigmatic retinitis pigmentosa-linked rhodopsin mutants

Retinitis pigmentosa (RP) is a blinding disease often associated with mutations in rhodopsin, a light-sensing G protein-coupled receptor and phospholipid scramblase. Most RP-associated mutations affect rhodopsin's activity or transport to disc membranes. Intriguingly, some mutations produce app...

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發表在:Nat Commun
Main Authors: Ploier, Birgit, Caro, Lydia N., Morizumi, Takefumi, Pandey, Kalpana, Pearring, Jillian N., Goren, Michael A., Finnemann, Silvia C., Graumann, Johannes, Arshavsky, Vadim Y., Dittman, Jeremy S., Ernst, Oliver P., Menon, Anant K.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059438/
https://ncbi.nlm.nih.gov/pubmed/27694816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12832
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