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highroad Is a Carboxypetidase Induced by Retinoids to Clear Mutant Rhodopsin-1 in Drosophila Retinitis Pigmentosa Models

Rhodopsins require retinoid chromophores for their function. In vertebrates, retinoids also serve as signaling molecules, but whether these molecules similarly regulate gene expression in Drosophila remains unclear. Here, we report the identification of a retinoid-inducible gene in Drosophila, highr...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Huang, Huai-Wei, Brown, Brian, Chung, Jaehoon, Domingos, Pedro M., Ryoo, Hyung Don
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832065/
https://ncbi.nlm.nih.gov/pubmed/29425495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.01.032
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