Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species

Protein aggregation into amyloid deposits and oxidative stress are key features of many neurodegenerative disorders including Parkinson's and Alzheimer's disease. We report here the creation of four highly sensitive bifunctional fluorescent probes, capable of H(2)O(2) and/or amyloid aggreg...

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Dades bibliogràfiques
Publicat a:R Soc Open Sci
Autors principals: Needham, Lisa-Maria, Weber, Judith, Fyfe, James W. B., Kabia, Omaru M., Do, Dung T., Klimont, Ewa, Zhang, Yu, Rodrigues, Margarida, Dobson, Christopher M., Ghandi, Sonia, Bohndiek, Sarah E., Snaddon, Thomas N., Lee, Steven F.
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society Publishing 2018
Matèries:
Chemistry
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830749/
https://ncbi.nlm.nih.gov/pubmed/29515860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.171399
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