Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species

Protein aggregation into amyloid deposits and oxidative stress are key features of many neurodegenerative disorders including Parkinson's and Alzheimer's disease. We report here the creation of four highly sensitive bifunctional fluorescent probes, capable of H(2)O(2) and/or amyloid aggreg...

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Spremljeno u:
Bibliografski detalji
Izdano u:R Soc Open Sci
Glavni autori: Needham, Lisa-Maria, Weber, Judith, Fyfe, James W. B., Kabia, Omaru M., Do, Dung T., Klimont, Ewa, Zhang, Yu, Rodrigues, Margarida, Dobson, Christopher M., Ghandi, Sonia, Bohndiek, Sarah E., Snaddon, Thomas N., Lee, Steven F.
Format: Artigo
Jezik:Inglês
Izdano: The Royal Society Publishing 2018
Teme:
Chemistry
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830749/
https://ncbi.nlm.nih.gov/pubmed/29515860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.171399
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