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Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species

Protein aggregation into amyloid deposits and oxidative stress are key features of many neurodegenerative disorders including Parkinson's and Alzheimer's disease. We report here the creation of four highly sensitive bifunctional fluorescent probes, capable of H(2)O(2) and/or amyloid aggreg...

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Detalhes bibliográficos
Publicado no:R Soc Open Sci
Main Authors: Needham, Lisa-Maria, Weber, Judith, Fyfe, James W. B., Kabia, Omaru M., Do, Dung T., Klimont, Ewa, Zhang, Yu, Rodrigues, Margarida, Dobson, Christopher M., Ghandi, Sonia, Bohndiek, Sarah E., Snaddon, Thomas N., Lee, Steven F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society Publishing 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830749/
https://ncbi.nlm.nih.gov/pubmed/29515860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.171399
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