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ThX – a next-generation probe for the early detection of amyloid aggregates

Neurodegenerative diseases such as Alzheimer's and Parkinson's are associated with protein misfolding and aggregation. Recent studies suggest that the small, rare and heterogeneous oligomeric species, formed early on in the aggregation process, may be a source of cytotoxicity. Thioflavin T...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Needham, Lisa-Maria, Weber, Judith, Varela, Juan A., Fyfe, James W. B., Do, Dung T., Xu, Catherine K., Tutton, Luke, Cliffe, Rachel, Keenlyside, Benjamin, Klenerman, David, Dobson, Christopher M., Hunter, Christopher A., Müller, Karin H., O'Holleran, Kevin, Bohndiek, Sarah E., Snaddon, Thomas N., Lee, Steven F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8159457/
https://ncbi.nlm.nih.gov/pubmed/34122915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc04730a
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