ThX – a next-generation probe for the early detection of amyloid aggregates

Neurodegenerative diseases such as Alzheimer's and Parkinson's are associated with protein misfolding and aggregation. Recent studies suggest that the small, rare and heterogeneous oligomeric species, formed early on in the aggregation process, may be a source of cytotoxicity. Thioflavin T...

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Dades bibliogràfiques
Publicat a:Chem Sci
Autors principals: Needham, Lisa-Maria, Weber, Judith, Varela, Juan A., Fyfe, James W. B., Do, Dung T., Xu, Catherine K., Tutton, Luke, Cliffe, Rachel, Keenlyside, Benjamin, Klenerman, David, Dobson, Christopher M., Hunter, Christopher A., Müller, Karin H., O'Holleran, Kevin, Bohndiek, Sarah E., Snaddon, Thomas N., Lee, Steven F.
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society of Chemistry 2020
Matèries:
Chemistry
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8159457/
https://ncbi.nlm.nih.gov/pubmed/34122915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc04730a
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