Llwytho...
Application of Receptor Theory to the Design and Use of Fixed-Proportion Mu-Opioid Agonist and Antagonist Mixtures in Rhesus Monkeys
Receptor theory predicts that fixed-proportion mixtures of a competitive, reversible agonist (e.g., fentanyl) and antagonist (e.g., naltrexone) at a common receptor [e.g., mu-opioid receptors (MORs)] will result in antagonist proportion-dependent decreases in apparent efficacy of the agonist/antagon...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | J Pharmacol Exp Ther |
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| Prif Awduron: | , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
The American Society for Pharmacology and Experimental Therapeutics
2018
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5830633/ https://ncbi.nlm.nih.gov/pubmed/29330156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.246439 |
| Tagiau: |
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