Targeting Nucleolin for better survival in diffuse large B-cell lymphoma

Anthracyclines have been a cornerstone in the cure of diffuse large B-cell lymphoma (DLBCL) and other hematological cancers. The ability of anthracyclines to eliminate DLBCL depends on the presence of topoisomerase-II-alpha (TopIIA), a DNA repair enzyme complex. We identified nucleolin as a novel bi...

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Publié dans:Leukemia
Auteurs principaux: Jain, Neeraj, Zhu, Haifeng, Khashab, Tamer, Ye, Qing, George, Bhawana, Mathur, Rohit, Singh, Ram Kumar, Berkova, Zuzana, Wise, Jillian F., Braun, Frank K., Wang, Xin, Patel, Keyur, Xu-Monette, Zijun Y., Courty, Jose, Young, Ken H., Sehgal, Lalit, Samaniego, Felipe
Format: Artigo
Langue:Inglês
Publié: 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829046/
https://ncbi.nlm.nih.gov/pubmed/28690315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2017.215
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