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Protein neddylation and its alterations in human cancers for targeted therapy

Neddylation, a post-translational modification that conjugates an ubiquitin-like protein NEDD8 to substrate proteins, is an important biochemical process that regulates protein function. The best-characterized substrates of neddylation are the cullin subunits of Cullin-RING ligases (CRLs), which, as...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Signal
Prif Awduron: Zhou, Lisha, Zhang, Wenjuan, Sun, Yi, Jia, Lijun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829022/
https://ncbi.nlm.nih.gov/pubmed/29331584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2018.01.009
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