Lanean...

Spontaneous excision and facilitated recovery as a control for phenotypes arising from RNA interference and other dominant transgenes

An essential control for genetic manipulation of microbes is the regeneration of the wild-type state and phenotype to validate that any mutant phenotypes are ‘on target’. For Leishmania gene knockouts, this is often done by re-expression of the target gene from episomal vectors, often bearing counte...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Biochem Parasitol
Egile Nagusiak: Brettmann, Erin A., Lye, Lon-Fye, Beverley, Stephen M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828908/
https://ncbi.nlm.nih.gov/pubmed/29357296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2018.01.004
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