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‘Transient’ Genetic Suppression Facilitates Generation of Hexose Transporter Null Mutants in Leishmania mexicana

The genome of Leishmania mexicana encompasses a cluster of three glucose transporter genes designated LmxGT1, LmxGT2, and LmxGT3. Functional and genetic studies of a cluster null mutant (Δlmxgt1-3) have dissected the roles of these proteins in Leishmania metabolism and virulence. However, null mutan...

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Detalhes bibliográficos
Main Authors: Feng, Xiuhong, Rodriguez-Contreras, Dayana, Polley, Tamsen, Lye, Lon-Fye, Scott, David, Burchmore, Richard J.S., Beverley, Stephen M., Landfear, Scott M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545093/
https://ncbi.nlm.nih.gov/pubmed/23170981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12106
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