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Normal aging induces A1-like astrocyte reactivity

The decline of cognitive function occurs with aging, but the mechanisms responsible are unknown. Astrocytes instruct the formation, maturation, and elimination of synapses, and impairment of these functions has been implicated in many diseases. These findings raise the question of whether astrocyte...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Clarke, Laura E., Liddelow, Shane A., Chakraborty, Chandrani, Münch, Alexandra E., Heiman, Myriam, Barres, Ben A.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828643/
https://ncbi.nlm.nih.gov/pubmed/29437957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1800165115
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