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Normal aging induces A1-like astrocyte reactivity

The decline of cognitive function occurs with aging, but the mechanisms responsible are unknown. Astrocytes instruct the formation, maturation, and elimination of synapses, and impairment of these functions has been implicated in many diseases. These findings raise the question of whether astrocyte...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Clarke, Laura E., Liddelow, Shane A., Chakraborty, Chandrani, Münch, Alexandra E., Heiman, Myriam, Barres, Ben A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828643/
https://ncbi.nlm.nih.gov/pubmed/29437957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1800165115
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