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Normal aging induces A1-like astrocyte reactivity

The decline of cognitive function occurs with aging, but the mechanisms responsible are unknown. Astrocytes instruct the formation, maturation, and elimination of synapses, and impairment of these functions has been implicated in many diseases. These findings raise the question of whether astrocyte...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Clarke, Laura E., Liddelow, Shane A., Chakraborty, Chandrani, Münch, Alexandra E., Heiman, Myriam, Barres, Ben A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828643/
https://ncbi.nlm.nih.gov/pubmed/29437957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1800165115
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