Human Cytomegalovirus Tegument Protein pp65 (pUL83) Dampens Type I Interferon Production by Inactivating the DNA Sensor cGAS without Affecting STING

The innate immune response plays a pivotal role during human cytomegalovirus (HCMV) primary infection. Indeed, HCMV infection of primary fibroblasts rapidly triggers strong induction of type I interferons (IFN-I), accompanied by proinflammatory cytokine release. Here, we show that primary human fore...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Biolatti, Matteo, Dell'Oste, Valentina, Pautasso, Sara, Gugliesi, Francesca, von Einem, Jens, Krapp, Christian, Jakobsen, Martin Roelsgaard, Borgogna, Cinzia, Gariglio, Marisa, De Andrea, Marco, Landolfo, Santo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2018
Gaiak:
Virus-Cell Interactions
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827387/
https://ncbi.nlm.nih.gov/pubmed/29263269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01774-17
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak