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The ubiquitin ligase ITCH coordinates small intestinal epithelial homeostasis by modulating cell proliferation, differentiation, and migration

Maintenance of the intestinal mucosa is driven by local signals that coordinate epithelial proliferation, differentiation, and turnover in order to separate antigenic luminal contents from the host’s immune system. Breaches in this barrier promote gastrointestinal pathologies ranging from inflammato...

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Detalhes bibliográficos
Publicado no:Differentiation
Main Authors: Mentrup, Heather L., Hartman, Amanda, Thames, Elizabeth L., Basheer, Wassim A., Matesic, Lydia E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826883/
https://ncbi.nlm.nih.gov/pubmed/29309986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.diff.2017.12.003
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