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Cardiomyocyte-Specific Overexpression of the Ubiquitin Ligase Wwp1 Contributes to Reduction in Connexin 43 and Arrhythmogenesis

Gap junctions (GJ) are intercellular channels composed of connexin subunits that play a critical role in a diverse number of cellular processes in all tissue types. In the heart, GJs mediate electrical coupling between cardiomyocytes and display mislocalization and/or downregulation in cardiac disea...

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Detalhes bibliográficos
Publicado no:J Mol Cell Cardiol
Main Authors: Basheer, Wassim A., Harris, Brett S., Mentrup, Heather L., Abreha, Measho, Thames, Elizabeth L., Lea, Jessica B., Swing, Deborah A., Copeland, Neal G., Jenkins, Nancy A., Price, Robert L., Matesic, Lydia E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641030/
https://ncbi.nlm.nih.gov/pubmed/26386426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.09.004
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