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The ubiquitin–protein ligase Itch regulates p73 stability

p73, a member of the p53 family of transcription factors, is upregulated in response to DNA damage, inducing cell cycle arrest and apoptosis. Besides indications that this p73 response is post-transcriptional, little is known about the underlying molecular mechanisms of p73 protein degradation. Ubiq...

詳細記述

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書誌詳細
主要な著者: Rossi, Mario, De Laurenzi, Vincenzo, Munarriz, Eliana, Green, Douglas R, Liu, Yun-Cai, Vousden, Karen H, Cesareni, Gianni, Melino, Gerry
フォーマット: Artigo
言語:Inglês
出版事項: 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC549609/
https://ncbi.nlm.nih.gov/pubmed/15678106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600444
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