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The ubiquitin–protein ligase Itch regulates p73 stability
p73, a member of the p53 family of transcription factors, is upregulated in response to DNA damage, inducing cell cycle arrest and apoptosis. Besides indications that this p73 response is post-transcriptional, little is known about the underlying molecular mechanisms of p73 protein degradation. Ubiq...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC549609/ https://ncbi.nlm.nih.gov/pubmed/15678106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600444 |
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