Recognition of RNA N(6)-methyladenosine by IGF2BP Proteins Enhances mRNA Stability and Translation

N (6)-methyladenosine (m(6)A) is the most prevalent modification in eukaryotic messenger RNAs (mRNAs) and is interpreted by its readers, such as YTH domain-containing proteins, to regulate mRNA fate. Here we report the insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs; including IGF2BP1/2/...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Cell Biol
Prif Awduron: Huang, Huilin, Weng, Hengyou, Sun, Wenju, Qin, Xi, Shi, Hailing, Wu, Huizhe, Zhao, Boxuan Simen, Mesquita, Ana, Liu, Chang, Yuan, Celvie L., Hu, Yueh-Chiang, Hüttelmaier, Stefan, Skibbe, Jennifer R., Su, Rui, Deng, Xiaolan, Dong, Lei, Sun, Miao, Li, Chenying, Nachtergaele, Sigrid, Wang, Yungui, Hu, Chao, Ferchen, Kyle, Greis, Kenneth D., Jiang, Xi, Wei, Minjie, Qu, Lianghu, Guan, Jun-Lin, He, Chuan, Yang, Jianhua, Chen, Jianjun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826585/
https://ncbi.nlm.nih.gov/pubmed/29476152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0045-z
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