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N(6)-methyladenosine Modulates Messenger RNA Translation Efficiency
N(6)-methyladenosine (m(6)A) is the most abundant internal modification in mammalian mRNA. This modification is reversible and non-stoichiometric and adds another layer to the dynamic control of mRNA metabolism. The stability of m(6)A-modified mRNA is regulated by an m(6)A reader protein, human YTHD...
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Izdano u: | Cell |
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Glavni autori: | , , , , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2015
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4825696/ https://ncbi.nlm.nih.gov/pubmed/26046440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.05.014 |
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