The dynamic N(1)-methyladenosine methylome in eukaryotic messenger RNA

Gene expression can be regulated post-transcriptionally through dynamic and reversible RNA modifications. A recent noteworthy example is N(6)-methyladenosine (m(6)A), which affects messenger RNA (mRNA) localization, stability, translation and splicing. Here we report on a new mRNA modification, N(1)...

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Udgivet i:Nature
Main Authors: Dominissini, Dan, Nachtergaele, Sigrid, Moshitch-Moshkovitz, Sharon, Peer, Eyal, Kol, Nitzan, Ben-Haim, Moshe Shay, Dai, Qing, Di Segni, Ayelet, Salmon-Divon, Mali, Clark, Wesley C., Zheng, Guanqun, Pan, Tao, Solomon, Oz, Eyal, Eran, Hershkovitz, Vera, Han, Dali, Doré, Louis C., Amariglio, Ninette, Rechavi, Gideon, He, Chuan
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842015/
https://ncbi.nlm.nih.gov/pubmed/26863196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature16998
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