Sugar-sweetened beverage intake associations with fasting glucose and insulin concentrations are not modified by selected genetic variants in a ChREBP-FGF21 pathway: a meta-analysis

AIMS/HYPOTHESIS: Sugar-sweetened beverages (SSBs) are a major dietary contributor to fructose intake. A molecular pathway involving the carbohydrate responsive element-binding protein (ChREBP) and the metabolic hormone fibroblast growth factor 21 (FGF21) may influence sugar metabolism and thereby co...

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Publicat a:Diabetologia
Autors principals: McKeown, Nicola M., Dashti, Hassan S., Ma, Jiantao, Haslam, Danielle E., Kiefte-de Jong, Jessica C., Smith, Caren E., Tanaka, Toshiko, Graff, Mariaelisa, Lemaitre, Rozenn N., Rybin, Denis, Sonestedt, Emily, Frazier-Wood, Alexis C., Mook-Kanamori, Dennis O., Li, Yanping, Wang, Carol A., Leermakers, Elisabeth T.M., Mikkilä, Vera, Young, Kristin L., Mukamal, Kenneth J., Cupples, L. Adrienne, Schulz, Christina-Alexandra, Chen, Tzu-An, Li-Gao, Ruifang, Huang, Tao, Oddy, Wendy H., Raitakari, Olli, Rice, Kenneth, Meigs, James B., Ericson, Ulrika, Steffen, Lyn M., Rosendaal, Frits R., Hofman, Albert, Kähönen, Mika, Psaty, Bruce M., Brunkwall, Louise, Uitterlinden, Andre G., Viikari, Jorma, Siscovick, David S., Seppälä, Ilkka, North, Kari E., Mozaffarian, Dariush, Dupuis, Josée, Orho-Melander, Marju, Rich, Stephen S., de Mutsert, Renée, Qi, Lu, Pennell, Craig E., Franco, Oscar H., Lehtimäki, Terho, Herman, Mark A.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826559/
https://ncbi.nlm.nih.gov/pubmed/29098321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-017-4475-0
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