NSG2 (ORF19.273) Encoding Protein Controls Sensitivity of Candida albicans to Azoles through Regulating the Synthesis of C14-Methylated Sterols

Antifungal azole drugs inhibit the synthesis of ergosterol and cause the accumulation of sterols containing a 14α-methyl group, which is related to the properties of cell membrane. Due to the frequent recurrence of fungal infections and clinical long-term prophylaxis, azole resistance is increasing...

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Vydáno v:Front Microbiol
Hlavní autoři: Lv, Quan-Zhen, Qin, Yu-Lin, Yan, Lan, Wang, Liang, Zhang, Chuyue, Jiang, Yuan-Ying
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826172/
https://ncbi.nlm.nih.gov/pubmed/29515531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.00218
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