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Stress-activated MAPKs and CRM1 regulate the subcellular localization of Net1A to control cell motility and invasion
The neuroepithelial cell transforming gene 1A (Net1A, an isoform of Net1) is a RhoA subfamily guanine nucleotide exchange factor (GEF) that localizes to the nucleus in the absence of stimulation, preventing it from activating RhoA. Once relocalized in the cytosol, Net1A stimulates cell motility and...
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| Publicado en: | J Cell Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Company of Biologists Ltd
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5826041/ https://ncbi.nlm.nih.gov/pubmed/29361525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.204644 |
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