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Regulation of Focal Adhesion Kinase Activation, Breast Cancer Cell Motility, and Amoeboid Invasion by the RhoA Guanine Nucleotide Exchange Factor Net1

Net1 is a RhoA guanine nucleotide exchange factor (GEF) that is overexpressed in a subset of human cancers and contributes to cancer cell motility and invasion in vitro. However, the molecular mechanism accounting for its role in cell motility and invasion has not been described. In the present work...

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Detalhes bibliográficos
Main Authors: Carr, Heather S., Zuo, Yan, Oh, Wonkyung, Frost, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700125/
https://ncbi.nlm.nih.gov/pubmed/23689132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00175-13
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