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Contributions of the RhoA guanine nucleotide exchange factor Net1 to polyoma middle T antigen-mediated mammary gland tumorigenesis and metastasis

BACKGROUND: The RhoA activating protein Net1 contributes to breast cancer cell proliferation, motility, and invasion in vitro, yet little is known about its roles in mammary gland tumorigenesis and metastasis. METHODS: Net1 knockout (KO) mice were bred to mice with mammary gland specific expression...

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Podrobná bibliografie
Vydáno v:Breast Cancer Res
Hlavní autoři: Zuo, Yan, Ulu, Arzu, Chang, Jeffrey T., Frost, Jeffrey A.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5956559/
https://ncbi.nlm.nih.gov/pubmed/29769144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-018-0966-2
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