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Revealing age-related changes of adult hippocampal neurogenesis using mathematical models

New neurons are continuously generated in the dentate gyrus of the adult hippocampus. This continuous supply of newborn neurons is important to modulate cognitive functions. Yet the number of newborn neurons declines with age. Increasing Wnt activity upon loss of dickkopf 1 can counteract both the d...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Development
Egile Nagusiak: Ziebell, Frederik, Dehler, Sascha, Martin-Villalba, Ana, Marciniak-Czochra, Anna
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Company of Biologists Ltd 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825879/
https://ncbi.nlm.nih.gov/pubmed/29229768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.153544
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