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Revealing age-related changes of adult hippocampal neurogenesis using mathematical models

New neurons are continuously generated in the dentate gyrus of the adult hippocampus. This continuous supply of newborn neurons is important to modulate cognitive functions. Yet the number of newborn neurons declines with age. Increasing Wnt activity upon loss of dickkopf 1 can counteract both the d...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Ziebell, Frederik, Dehler, Sascha, Martin-Villalba, Ana, Marciniak-Czochra, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825879/
https://ncbi.nlm.nih.gov/pubmed/29229768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.153544
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