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Mathematical modelling of adult hippocampal neurogenesis: effects of altered stem cell dynamics on cell counts and bromodeoxyuridine-labelled cells

In the adult hippocampus, neurogenesis—the process of generating mature granule cells from adult neural stem cells—occurs throughout the entire lifetime. In order to investigate the involved regulatory mechanisms, knockout (KO) experiments, which modify the dynamic behaviour of this process, were co...

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Detalhes bibliográficos
Main Authors: Ziebell, Frederik, Martin-Villalba, Ana, Marciniak-Czochra, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973376/
https://ncbi.nlm.nih.gov/pubmed/24598209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2014.0144
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