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Estimating Dormant and Active Hematopoietic Stem Cell Kinetics through Extensive Modeling of Bromodeoxyuridine Label-Retaining Cell Dynamics

Bone marrow hematopoietic stem cells (HSCs) are responsible for both lifelong daily maintenance of all blood cells and for repair after cell loss. Until recently the cellular mechanisms by which HSCs accomplish these two very different tasks remained an open question. Biological evidence has now bee...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: van der Wath, Richard C., Wilson, Anne, Laurenti, Elisa, Trumpp, Andreas, Liò, Pietro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745578/
https://ncbi.nlm.nih.gov/pubmed/19771180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006972
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