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Revealing age-related changes of adult hippocampal neurogenesis using mathematical models

New neurons are continuously generated in the dentate gyrus of the adult hippocampus. This continuous supply of newborn neurons is important to modulate cognitive functions. Yet the number of newborn neurons declines with age. Increasing Wnt activity upon loss of dickkopf 1 can counteract both the d...

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Dettagli Bibliografici
Pubblicato in:Development
Autori principali: Ziebell, Frederik, Dehler, Sascha, Martin-Villalba, Ana, Marciniak-Czochra, Anna
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825879/
https://ncbi.nlm.nih.gov/pubmed/29229768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.153544
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