Engineered aglycosylated full-length IgG Fc variants exhibiting improved FcγRIIIa binding and tumor cell clearance

Lignende værker

• Engineering Aglycosylated IgG Variants with Wild-type or Improved Binding Affinity to Human Fc gamma RIIA and Fc gamma RIIIAs
  af: Chen, Tiffany F., et al.
  Udgivet: (2017)
• IgG antibodies to dengue enhanced for FcγRIIIA binding determine disease severity
  af: Wang, Taia T., et al.
  Udgivet: (2017)
• Clearance of red cells by monoclonal IgG3 anti-D in vivo is affected by the VF polymorphism of Fcγ RIIIa (CD16)
  af: KUMPEL, B M, et al.
  Udgivet: (2003)
• The N-linked oligosaccharide at FcγRIIIa Asn-45: an inhibitory element for high FcγRIIIa binding affinity to IgG glycoforms lacking core fucosylation
  af: Shibata-Koyama, Mami, et al.
  Udgivet: (2009)
• Aglycosylated IgG variants expressed in bacteria that selectively bind FcγRI potentiate tumor cell killing by monocyte-dendritic cells
  af: Jung, Sang Taek, et al.
  Udgivet: (2010)