Nalaganje...

The N-linked oligosaccharide at FcγRIIIa Asn-45: an inhibitory element for high FcγRIIIa binding affinity to IgG glycoforms lacking core fucosylation

Human leukocyte receptor IIIa (FcγRIIIa) plays an important role in mediating therapeutic antibodies’ antibody-dependent cellular cytotoxicity (ADCC), which is closely related to the clinical efficacy of anticancer processes in humans in vivo. The removal of the core fucose from oligosaccharides att...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Shibata-Koyama, Mami, Iida, Shigeru, Okazaki, Akira, Mori, Katsuhiro, Kitajima-Miyama, Kazuko, Saitou, Seiji, Kakita, Shingo, Kanda, Yutaka, Shitara, Kenya, Kato, Koichi, Satoh, Mitsuo
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2639328/
https://ncbi.nlm.nih.gov/pubmed/18952826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwn110
Oznake: Označite
Brez oznak, prvi označite!