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Structural Characterization of GASDALIE Fc Bound to the Activating Fc receptor FcγRIIIa

The Fc region of Immunoglobulin G (IgG) initiates inflammatory responses such as antibody-dependent cell-mediated cytotoxicity (ADCC) through binding to activating Fc receptors (FcγRI, FcγRIIa, FcγRIIIa). These receptors are expressed on the surface of immune cells including macrophages, dendritic c...

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Dettagli Bibliografici
Pubblicato in:J Struct Biol
Autori principali: Ahmed, Alysia A., Keremane, Sravya R., Vielmetter, Jost, Bjorkman, Pamela J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769027/
https://ncbi.nlm.nih.gov/pubmed/26850169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2016.02.001
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