FcγRIIIa receptor polymorphism influences NK cell mediated ADCC activity against HIV

BACKGROUND: HIV-specific Antibody Dependent Cell Cytotoxicity (ADCC) has shown to be important in HIV control and resistance. The ADCC is mediated primarily by natural killer cell activated through the binding of FcγRIIIa receptor to the Fc portion of antibody bound to the antigen expressed on the i...

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Vydáno v:BMC Infect Dis
Hlavní autoři: Talathi, Sneha Pramod, Shaikh, Nawaj Najir, Pandey, Sudhanshu Shekhar, Saxena, Vandana Ashish, Mamulwar, Megha Sunil, Thakar, Madhuri Rajeev
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916223/
https://ncbi.nlm.nih.gov/pubmed/31842762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-019-4674-z
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