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Structural Characterization of GASDALIE Fc Bound to the Activating Fc receptor FcγRIIIa
The Fc region of Immunoglobulin G (IgG) initiates inflammatory responses such as antibody-dependent cell-mediated cytotoxicity (ADCC) through binding to activating Fc receptors (FcγRI, FcγRIIa, FcγRIIIa). These receptors are expressed on the surface of immune cells including macrophages, dendritic c...
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| Veröffentlicht in: | J Struct Biol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4769027/ https://ncbi.nlm.nih.gov/pubmed/26850169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2016.02.001 |
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