Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes

B cell follicles in secondary lymphoid tissues represent an immune privileged sanctuary for AIDS viruses, in part because cytotoxic CD8(+) T cells are mostly excluded from entering the follicles that harbor infected T follicular helper (T(FH)) cells. We studied the effects of native heterodimeric IL...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS Pathog
Egile Nagusiak: Watson, Dionysios C., Moysi, Eirini, Valentin, Antonio, Bergamaschi, Cristina, Devasundaram, Santhi, Fortis, Sotirios P., Bear, Jenifer, Chertova, Elena, Bess, Julian, Sowder, Ray, Venzon, David J., Deleage, Claire, Estes, Jacob D., Lifson, Jeffrey D., Petrovas, Constantinos, Felber, Barbara K., Pavlakis, George N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2018
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825155/
https://ncbi.nlm.nih.gov/pubmed/29474450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006902
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