Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes

B cell follicles in secondary lymphoid tissues represent an immune privileged sanctuary for AIDS viruses, in part because cytotoxic CD8(+) T cells are mostly excluded from entering the follicles that harbor infected T follicular helper (T(FH)) cells. We studied the effects of native heterodimeric IL...

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Dades bibliogràfiques
Publicat a:PLoS Pathog
Autors principals: Watson, Dionysios C., Moysi, Eirini, Valentin, Antonio, Bergamaschi, Cristina, Devasundaram, Santhi, Fortis, Sotirios P., Bear, Jenifer, Chertova, Elena, Bess, Julian, Sowder, Ray, Venzon, David J., Deleage, Claire, Estes, Jacob D., Lifson, Jeffrey D., Petrovas, Constantinos, Felber, Barbara K., Pavlakis, George N.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825155/
https://ncbi.nlm.nih.gov/pubmed/29474450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006902
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