Clonally expanded γδ T cells protect against Staphylococcus aureus skin reinfection

The mechanisms that mediate durable protection against Staphylococcus aureus skin reinfections are unclear, as recurrences are common despite high antibody titers and memory T cells. Here, we developed a mouse model of S. aureus skin reinfection to investigate protective memory responses. In contras...

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Publicat a:J Clin Invest
Autors principals: Dillen, Carly A., Pinsker, Bret L., Marusina, Alina I., Merleev, Alexander A., Farber, Orly N., Liu, Haiyun, Archer, Nathan K., Lee, Da B., Wang, Yu, Ortines, Roger V., Lee, Steven K., Marchitto, Mark C., Cai, Shuting S., Ashbaugh, Alyssa G., May, Larissa S., Holland, Steven M., Freeman, Alexandra F., Miller, Loren G., Yeaman, Michael R., Simon, Scott I., Milner, Joshua D., Maverakis, Emanual, Miller, Lloyd S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824877/
https://ncbi.nlm.nih.gov/pubmed/29400698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI96481
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